After three decades since the 1989 film, Wayne Szalinski’s son, Nick Szalinski, accidentally shrinks his kids.
| Directing | Joe Johnston | Director |
| Production | David Hoberman | Producer |
| Production | Todd Lieberman | Producer |
| Writing | Todd Rosenberg | Screenplay |
| Production | James D. Bissell | Production Designer |
| Writing | Josh Gad | Story |
| Writing | Ryan Dixon | Story |
| Writing | Ian Helfer | Story |
| Writing | Jay Reiss | Story |
| Production | Zoe Kent | Executive Producer |
| Production | Sam Dickeman | Executive Producer |
| Production | Alexander F. Young | Executive Producer |
| Camera | Shelly Johnson | Director of Photography |