Raoul Duke and his attorney Dr. Gonzo drive a red convertible across the Mojave desert to Las Vegas with a suitcase full of drugs to cover a motorcycle race. As their consumption of drugs increases at an alarming rate, the stoned duo trash their hotel room and fear legal repercussions. Duke begins to drive back to L.A., but after an odd run-in with a cop, he returns to Sin City and continues his wild drug binge.
| Editing | Lesley Walker | Editor |
| Art | Nancy Haigh | Set Decoration |
| Production | Patrick Cassavetti | Producer |
| Directing | Terry Gilliam | Director |
| Production | Margery Simkin | Casting |
| Production | Laila Nabulsi | Producer |
| Costume & Make-Up | Julie Weiss | Costume Design |
| Production | Stephen Nemeth | Producer |
| Camera | Nicola Pecorini | Director of Photography |
| Art | Chris Gorak | Art Direction |
| Art | Alex McDowell | Production Design |
| Writing | Terry Gilliam | Screenplay |
| Production | Elliot Lewis Rosenblatt | Co-Producer |
| Art | Ronald Day | Painter |
| Crew | JoAnn Fregalette Jansen | Choreographer |
| Art | Lynn Christopher | Set Designer |
| Art | Glen Hanz | Sculptor |
| Art | Mark Weissenfluh | Leadman |
| Art | Mark Blumenthal | Standby Painter |
| Camera | Frank Perl | Camera Operator |
| Writing | Alex Cox | Screenplay |
| Writing | Tony Grisoni | Screenplay |
| Writing | Tod Davies | Screenplay |
| Production | John Jergens | Associate Producer |
| Production | Harold Bronson | Executive Producer |
| Production | Richard Foos | Executive Producer |
| Sound | Ray Cooper | Original Music Composer |
| Crew | Rob Bottin | Makeup Effects |
| Costume & Make-Up | Bridget Cook | Hairstylist |
| Costume & Make-Up | Olga Ishkhanova | Seamstress |
| Costume & Make-Up | Bill Fletcher | Wigmaker |
| Crew | Maureen Kropf | Scenic Artist |
| Crew | Michael Singer | Unit Publicist |
| Production | Deborah Ricketts | Researcher |
| Crew | Randy Benjamin | Picture Car Coordinator |
| Sound | Peter Pennell | Supervising Sound Editor |
| Visual Effects | Michael Cooper | Visual Effects Coordinator |
| Art | Tani Kunitake | Production Illustrator |
| Crew | Michael Solinger | Post Production Supervisor |
| Crew | Matt Langenbach | Stand In |
| Lighting | James Babineaux | Best Boy Electric |
| Visual Effects | Ray Svedin | Special Effects Supervisor |
| Costume & Make-Up | Eden Clark Coblenz | Costume Supervisor |
| Sound | Jay Meagher | Production Sound Mixer |
| Crew | Kelly Joe Dugan | Stunts |
| Costume & Make-Up | Linda S. Cormany | Set Costumer |
| Crew | Pedro Amaya | Driver |
| Crew | Roanne Moore | Post Production Assistant |
| Camera | Łukasz Bielan | First Assistant Camera |
| Crew | Noon Orsatti | Stunt Coordinator |
| Crew | James Lowder | Transportation Coordinator |
| Production | Pearl A. Lucero | Production Coordinator |
| Camera | Peter Mountain | Still Photographer |
| Directing | Karon May | Script Supervisor |
| Sound | Randy Smith | Boom Operator |
| Art | Andrea Carter | Art Department Coordinator |
| Art | Frank McEldowney | Greensman |
| Camera | Nicola Pecorini | Steadicam Operator |
| Editing | David Rees | Color Timer |
| Art | Dan Pemberton | Construction Coordinator |
| Visual Effects | Kent Houston | Visual Effects Supervisor |
| Costume & Make-Up | Kimberly Adams | Assistant Costume Designer |
| Crew | Gloria M. Fujita | Set Medic |
| Crew | Jimmy Bennett | Set Production Assistant |
| Lighting | Reynaldo Barrera | Electrician |
| Production | Molly Allen | Location Manager |
| Art | Dianne Chadwick | Art Department Assistant |
| Crew | Gary Gingold | Craft Service |
| Crew | Steve Galich | Special Effects Coordinator |
| Crew | Ian Kelly | Video Assist Operator |
| Sound | Dominic Lester | Sound Re-Recording Mixer |
| Art | Tom Lifsey | Construction Foreman |
| Crew | Pat Stubbs | Transportation Co-Captain |
| Production | Mark Indig | Unit Production Manager |
| Crew | Earl F. Betts | Propmaker |
| Lighting | Christopher Lyons | Gaffer |
| Sound | Kevin Lane | Music Editor |
| Sound | Martin Cantwell | Assistant Sound Editor |
| Camera | Peter Chrimes | Key Grip |
| Costume & Make-Up | Cheryl Ann Nick | Key Makeup Artist |
| Art | Paige Augustine | Set Dresser |
| Production | Nancy Restuccia | Assistant Production Coordinator |
| Directing | Christina Fong | Second Assistant Director |
| Camera | Lila Byall | Camera Loader |
| Camera | Carlos M. Gallardo | Dolly Grip |
| Sound | Caroline Dale | Musician |
| Sound | Joe Gallagher | ADR Editor |
| Camera | Michael Mick Armstrong | Grip |
| Costume & Make-Up | Rebeka L. Roberts | Ager/Dyer |
| Production | Carmen Cuba | Casting Assistant |
| Sound | Stephen Bridgewater | ADR Supervisor |
| Costume & Make-Up | John Linsmeier | Key Costumer |
| Directing | Philip A. Patterson | First Assistant Director |
| Sound | David Acord | Utility Sound |
| Costume & Make-Up | Lisa Rocco | Makeup Artist |
| Sound | Bob Risk | Foley Editor |
| Sound | J.R. Westen | ADR Mixer |
| Crew | Sav Akyüz | Intern |
| Directing | Bruce Logan | Second Unit Director |
| Costume & Make-Up | Amy Gilliam | Wardrobe Assistant |
| Editing | Jeremy Hume | Assistant Editor |
| Art | P. Scott Bailey | Swing |
| Crew | Jimmy Ortega | Stunt Double |
| Production | Keli Craig | Production Assistant |
| Art | Martin Charles | Graphic Designer |
| Camera | Sonja Rom | Camera Production Assistant |
| Production | Susan Giordano | First Assistant Accountant |
| Production | Serena Baker | Location Assistant |
| Directing | Seth Edelstein | Second Second Assistant Director |
| Costume & Make-Up | Bryan Birge | Costumer |
| Production | R. Scott Poole | Assistant Location Manager |
| Production | Kristen Felan | Payroll Accountant |
| Camera | Vidal Cohen | Best Boy Grip |
| Camera | Warren Feldman | Second Assistant Camera |
| Production | Jenni Wieland | Second Assistant Accountant |
| Crew | Joe Barden | Special Effects Assistant |
| Camera | Steve Itano | First Assistant "A" Camera |
| Crew | Jose Gonzales | Catering |
| Production | Alisa Moeller | Assistant Production Coordinator |
| Sound | Paul Carr | ADR Recordist |
| Sound | Alan Paley | Dialogue Editor |
| Art | Will Blount | Property Master |
| Crew | Ernie F. Orsatti | Stunts |
| Writing | Hunter S. Thompson | Novel |
